Idiopathic, non-infectious, non-erosive arthritis in a bitch

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Abstract
A 2 1/2-year-old Cavalier King Charles Spaniel bitch was examined because of recurring episodes of lameness and joint swelling over a period of 2 years. Clinical examination, radiography, serology, joint-fluid analysis and histopathology of the joint capsule led to a diagnosis of idiopathic, non-infectious, non-erosive arthritis. Combination therapy with prednisolone, cyclophosphamide and azothioprine produced a rapid improvement in the dog's condition. The features of this disease and its relationship to rheumatoid arthritis and systemic lupus erythematosis are discussed.

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