Streptomycin Treatment of Pulmonary Infections

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Abstract
ALTHOUGH pulmonary infections caused by gram-negative bacilli are much less frequent than those caused by gram-positive cocci, they are generally severe and often leave serious damage in the lungs of patients who recover. Their importance has become particularly evident since the advent of the sulfonamides and penicillin, which have produced highly favorable results in pneumococcal, streptococcal and staphylococcal pneumonias but have not materially influenced those due to gram-negative bacilli.Since the original report by Schatz, Bugie and Waksman1 on streptomycin and its antibacterial action against certain gram-negative bacilli, numerous studies have confirmed the marked effect of this antibiotic against most . . .