Screening for Multiple Endocrine Neoplasia Type 2A with DNA-Polymorphism Analysis
- 12 October 1989
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 321 (15) , 996-1001
- https://doi.org/10.1056/nejm198910123211502
Abstract
Multiple endocrine neoplasia type 2a has been shown to be genetically linked to a locus near the centromere of chromosome 10. The availability of polymorphic DNA probes for the region permits the use of restriction-fragment–length polymorphisms (RFLP) to identify carriers of the gene for this cancer syndrome.This publication has 21 references indexed in Scilit:
- Linked markers flanking the gene for multiple endocrine neoplasia type 2AGenomics, 1989
- The Clinical Outcome of Prospective Screening for Multiple Endocrine Neoplasia Type 2ANew England Journal of Medicine, 1988
- SCREENING MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A FAMILIES USING DNA MARKERSThe Lancet, 1988
- Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkageNature, 1987
- A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10Nature, 1987
- Exclusion of linkage of loci on chromosome 19 with multiple endocrine neoplasia, type 2Cytogenetic and Genome Research, 1987
- Familial medullary thyroid carcinoma without associated endocrinopathies: A distinct clinical entityBritish Journal of Surgery, 1986
- Genetic Aspects of Multiple Endocrine NeoplasiaAnnual Review of Medicine, 1984
- Natural History of Familial Medullary Thyroid CarcinomaNew England Journal of Medicine, 1978
- Medullary Thyroid CarcinomaAnnals of Surgery, 1978