Abstract
The presence of at least 5 different types of ionizable groups on the surface of normal human lymphocytes on a per-cell-basis has been established. Two possible arrangements of these groups have been put forward. These surface groups (positively and negatively charged) may provide a molecular basis for establishing differences, if any, between types of lymphocytes. The complex reactions taking place on the surface of lymphocytes involved in immune processes are of considerable interest in health and disease.

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