Theknotted1-like homeobox geneBREVIPEDICELLUSregulates cell differentiation by modulating metabolic pathways
Open Access
- 1 January 2003
- journal article
- Published by Cold Spring Harbor Laboratory in Genes & Development
- Vol. 17 (17) , 2088-2093
- https://doi.org/10.1101/gad.1120003
Abstract
Members of theKNOXgene family have important roles in plant meristems by regulating cell division and differentiation.BREVIPEDICELLUS(BP), one of sevenKNOXgenes inArabidopsis, has a primary role in internode patterning. We carried out a comparison of RNA expression profiles between wild-type seedlings andbpmutants at a developmental stage prior to a visible phenotypic difference. Transcript differences were found for a number of genes in cell wall biosynthesis, especially genes in the lignin pathway. The regulation of lignin biosynthesis byBPwas demonstrated by observing increased lignin deposition inbpmutants following bolting, decreased lignification in plants overexpressingBP, and aberrant lignin deposition in discrete regions of thebpstem. Furthermore, we showed that BP binds promoters of some genes in the lignin pathway. Our results provide a metabolic fingerprint forBPand identify the lignin pathway as one of the coordinate processes thatBPregulates.Keywords
This publication has 27 references indexed in Scilit:
- Overexpression of KNAT1 in Lettuce Shifts Leaf Determinate Growth to a Shoot-Like Indeterminate Growth Associated with an Accumulation of Isopentenyl-Type CytokininsPlant Physiology, 2001
- Control of Shoot Cell Fate: Beyond HomeoboxesPlant Cell, 2001
- Activation Tagging Identifies a Conserved MYB Regulator of Phenylpropanoid BiosynthesisPlant Cell, 2000
- Lignin genetic engineering revisitedPlant Science, 1999
- Tracheary Element Differentiation Uses a Novel Mechanism Coordinating Programmed Cell Death and Secondary Cell Wall Synthesis1Plant Physiology, 1999
- The AmMYB308 and AmMYB330 Transcription Factors from Antirrhinum Regulate Phenylpropanoid and Lignin Biosynthesis in Transgenic TobaccoPlant Cell, 1998
- KNAT1 induces lobed leaves with ectopic meristems when overexpressed in Arabidopsis.Plant Cell, 1996
- A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of ArabidopsisNature, 1996
- Expression of a flower-specific Myb protein in leaf cells using a viral vector causes ectopic activation of a target promoter.Proceedings of the National Academy of Sciences, 1995
- A knotted1-like homeobox gene in Arabidopsis is expressed in the vegetative meristem and dramatically alters leaf morphology when overexpressed in transgenic plants.Plant Cell, 1994