The inhibition of glucolysis by glyceraldehyde

Abstract
Glycolysis in liver, a glycogen-fermenting tissue, was not inhibited by high concs. of glyceraldehyde. It was confirmed that in muscle extract glycolysis of starch was not greatly inhibited by high concs. of glyceraldehyde, but that glucolysis by this system in the presence of hexokinase was completely inhibited by 0.003 M glyceraldehyde. This inhibition was reversed by a small excess of hexokinase. It was also reversed, as was the case in slices of glucolysing tissues, by very small amts. of pyruvic acid.

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