Mechanism of Action of Nalidixic Acid on Escherichia coli V. Possible Mutagenic Effect
- 1 February 1966
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 91 (2) , 780-+
- https://doi.org/10.1128/jb.91.2.780-783.1966
Abstract
Cook, Thomas M. , (Sterling-Winthrop Research Institute, Rensselaer, N.Y.), William A. Goss, and William H. Deitz . Mechanism of action of nalidixic acid on Escherichia coli . V. Possible mutagenic effect. J. Bacteriol. 91: 780–783. 1966.—With a streptomycin-dependent organism, Escherichia coli ATCC 11143, it has been shown that exposure to nalidixic acid, under conditions permitting some bactericidal action, results in an increased number of streptomycin-independent bacteria among the survivors. This effect is evident only with proliferating cultures, and is related to the concentration of nalidixic acid and the duration of exposure.This publication has 6 references indexed in Scilit:
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