Brain Scintigraphy in Recurrent Medulloblastoma

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Abstract
Twenty-three patients with previously treated medulloblastoma had brain scintigrams during evaluation for recurrent or metastatic tumor. The scintigrams revealed posterior fossa recurrence in 15 patients and supratentorial metastases in 9. Only 1 of the latter was clinically suspected. Two subdural hematomas and 1 calvarial metastasis were also detected. Comparison with other diagnostic evidence shows agreement in 13 of 14 cases (93%) for posterior fossa recurrence of 8/10 (80%) for supratentiorial masses. Brain scintigraphy appears to be a sensitive and specific test for the detection of recurrence and metastasis in patients with treated medulloblastoma.

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