Chemistry of acetylenic ethers. Part 89: The reaction of organolithium compounds with 1‐alkynyl ethers
- 1 January 1968
- journal article
- research article
- Published by Wiley in Recueil des Travaux Chimiques des Pays-Bas
- Vol. 87 (1) , 69-72
- https://doi.org/10.1002/recl.19680870112
Abstract
Disubstituted acetylenes C4H9C≡CR are produced in the reaction of 1‐ethoxy‐1‐hexyne C4H9C≡COC2H5 with organolithium or Grignard compounds RLi or RMgBr. The yields are moderate to satisfactory. Ethoxyethyne HC≡COC2H5 and phenyllithium C6H5Li afford phenylacetylene HC≡CC6H5 (after hydrolysis) in moderate yield.The formation of acetylenes probably proceeds by an addition‐elimination mechanism.Keywords
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