Rational Design of Non-Hydroxamate Histone Deacetylase Inhibitors
- 1 May 2006
- journal article
- review article
- Published by Bentham Science Publishers Ltd. in Mini-Reviews in Medicinal Chemistry
- Vol. 6 (5) , 515-526
- https://doi.org/10.2174/138955706776876186
Abstract
While most inhibitors of histone deacetylases (HDACs) are hydroxamic acid derivatives, several nonhydroxamates have recently been developed as inhibitors and attracted quite a deal of attention. In this review, we present the rational design, inhibitory effect and antiproliferative activity of non-hydroxamate HDAC inhibitors.Keywords
This publication has 0 references indexed in Scilit: