Transforming growth factor β1 acts as an inducer of matrix metalloproteinase expression and activity in human bone-metastasizing cancer cells
- 1 January 1999
- journal article
- Published by Springer Nature in Clinical & Experimental Metastasis
- Vol. 17 (1) , 33-42
- https://doi.org/10.1023/a:1026404227624
Abstract
Bone metastases are a common complication in prostate and breast cancer patients. It leads to extensive morbidity and eventually mortality. Matrix metalloproteinases (MMPs) are known to be involved...Keywords
This publication has 49 references indexed in Scilit:
- Thrombospondin and transforming growth factor-beta 1 increase expression of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in human MDA-MB-231 breast cancer cellsCancer, 1995
- Bone and cancer: Pathophysiology and treatment of metastasesBone, 1995
- Relationship between actions of transforming growth factor (TGF)‐β and cell surface expression of its receptors in clonal osteoblastic cellsJournal of Cellular Physiology, 1995
- Matrix Metalloproteinase Gene ExpressionaAnnals of the New York Academy of Sciences, 1994
- Regulation of the levels of three transforming growth factor β mRNAs by estrogen and their effects on the proliferation of human breast cancer cellsMolecular and Cellular Endocrinology, 1993
- Different Signals Mediate Transforming Growth Factor-β1-Induced Growth Inhibition and Extracellular Matrix Production in Prostatic Carcinoma CellsExperimental Cell Research, 1993
- DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled waterAnalytical Biochemistry, 1990
- Accumulation, localization, and compartmentation of transforming growth factor beta during endochondral bone development.The Journal of cell biology, 1988
- Development of skeletal metastasis by human prostate cancer in athymic nude miceClinical & Experimental Metastasis, 1988
- Metastatic potential correlates with enzymatic degradation of basement membrane collagenNature, 1980