Analyzing protein structure and function using ancestral gene reconstruction
- 21 April 2010
- journal article
- review article
- Published by Elsevier in Current Opinion in Structural Biology
- Vol. 20 (3) , 360-366
- https://doi.org/10.1016/j.sbi.2010.03.005
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Exploring protein fitness landscapes by directed evolutionNature Reviews Molecular Cell Biology, 2009
- An epistatic ratchet constrains the direction of glucocorticoid receptor evolutionNature, 2009
- Enzyme (re)design: lessons from natural evolution and computationCurrent Opinion in Chemical Biology, 2009
- Epistasis — the essential role of gene interactions in the structure and evolution of genetic systemsNature Reviews Genetics, 2008
- Elucidation of phenotypic adaptations: Molecular analyses of dim-light vision proteins in vertebratesProceedings of the National Academy of Sciences, 2008
- Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthasesNature Chemical Biology, 2008
- Robustness–epistasis link shapes the fitness landscape of a randomly drifting proteinNature, 2006
- Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptorsProceedings of the National Academy of Sciences, 2006
- Protein stability promotes evolvabilityProceedings of the National Academy of Sciences, 2006
- Natural Selection and the Concept of a Protein SpaceNature, 1970