• 1 January 1976
    • journal article
    • research article
    • Vol. 40  (3) , 221-227
Abstract
Pneumonitis was induced in claves by exposure to aerosols of M. faeni with or without prior sensitization of the animals by s.c. injection of antigen. The pneumonitis primarily involved centrolobular areas and was characterized by alveolar septal thickening and loss of air space by cellular infiltration. Vasculitis and focal hemorrhage occurred in certain individuals and hemoproteinaceous exudate appeared within septa and alveolar lumina. The pneumonitis was compared with human farmer''s lung, penumonitis of housed cattle and other experimental hypersensitivity pneumonitides.