Familial Hemorrhagic Telangiectasia

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Abstract
THE occurrence of epistaxis in association with developmental anomalies of the blood vessels was first mentioned by Sutton1 in 1864. Babington2 described hereditary epistaxis in 1865. Thirty-one years later Rendu3 reported the same condition in a patient with cutaneous angiomas. The classic monograph of Sir William Osler4 in 1901 on a form of familial recurrent epistaxis associated with multiple telangiectases of the skin and mucous membranes did much to establish the syndrome as a clinical entity. Weber5 presented an account of another case of this rare disorder in 1907. Today, the Rendu—Osler—Weber disease, often referred to as Osler's disease, is . . .

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