Streptomycin in Treatment of Experimental Trypanosomiasis in White Mice and Chick Embryos.
- 1 April 1947
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 64 (4) , 391-393
- https://doi.org/10.3181/00379727-64-15805
Abstract
White mice and chick embryos were infected with Trypanosoma brucei, T. equiperidum and T. hippicum. After a lapse of 24-36 hrs., streptomycin was administered subcut. to the mice and was injd. into the yolk sac of the chick embryos. Each mouse received a total of 16,000 U. and each chick embryo, a total of 40,000 U. of streptomycin. The course of the disease was followed by microscopic examination of blood specimens taken at regular intervals. As far as could be determined, streptomycin did not alter the course of the infections or prolong the life of the treated mice or embryos.Keywords
This publication has 2 references indexed in Scilit:
- Isolation of an Antibiotic Agent Derived from a Phycomyces Active in vitro Against Trypanosoma eguiperdum.Experimental Biology and Medicine, 1946
- Rapid and Sterilizing Effect of Penicillin Sodium in Experimental Relapsing Fever Infections and Its Ineffectiveness in the Treatment of Trypanosomiasis ( Trypanosoma lewisi ) and ToxoplasmosisScience, 1944