Application of the polymerase chain reaction for the detection of HIV in specimens from newborn screening programs
- 1 August 1994
- journal article
- Published by Wiley in Acta Paediatrica
- Vol. 83 (s400) , 29-30
- https://doi.org/10.1111/j.1651-2227.1994.tb13330.x
Abstract
The use of the polymerase chain reaction (PCR) permits detection of HIV proviral DNA in the universally collected "dried blood spot specimens" of newborn screening programs. Detection of HIV proviral DNA among the annual cohorts of seropositive specimens from ongoing anonymous newborn HIV seroprevalence studies can provide a laboratory-based estimate of maternal-infant transmission rates. Preliminary data suggest that maternal-infant transmission rates may be higher in areas where the newborn seroprevalence rates are highest.Keywords
This publication has 2 references indexed in Scilit:
- Identifying human immunodeficiency virus infection at birth: Application of polymerase chain reaction to Guthrie cardsThe Journal of Pediatrics, 1993
- Perinatally acquired human immunodeficiency virus infectionThe Pediatric Infectious Disease Journal, 1992