Blue Baby Due to Methemoglobinemia

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Abstract
IN addition to congenital heart disease, with right-to-left shunts, and chronic lung disease, cyanosis in babies can be caused by methemoglobinemia. The congenital variety, of course, is lifelong, but several toxins may produce an acute, acquired variety. Nitrites (used as food preservatives or in well water), aniline dyes, acetanilid, pyridium, dinitrophenol and potassium chlorate‡ have all been recognized as producing this. Recently, benzocaine and its derivatives have been added to this list, as the following case§ demonstrates.A 1-month-old male infant was admitted to the hospital because of increasing blue color, restlessness and irritability. He had been well except for . . .

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