The Amino‐Acid Sequence of a Peptide (PS‐1) from Drosophila funebris: A Paragonial Peptide from Males which Reduces the Receptivity of the Female
Open Access
- 1 April 1975
- journal article
- Published by Wiley in European Journal of Biochemistry
- Vol. 52 (3) , 521-529
- https://doi.org/10.1111/j.1432-1033.1975.tb04023.x
Abstract
The substance, PS-1, produced in the paragonial gland of adult male Drosophila funebris influences the mating behavior of virgin female flies after injection. The substance was isolated and characterized as a 27-residue peptide. The complete amino acid sequence was determined by manual sequence analysis of tryptic peptides, automated Edman degradation, and carboxypeptidase A digestion. The sequence is Asp-ValLeu-Pro-Ser-Ala-Asn-Ala-Asn-Ala-Asn-Asn-Gln-Arg-Thr-Ala-Ala-Ala-Lys-Pro-Gln-Ala-Asn-Ala-Glu-Ala-Ser-Ser. The ratio of Val: Leu in the second position of the sequence is 7:3. This is the first detailed report on an insect peptide which causes a biological response in the opposite sex following mating.Keywords
This publication has 18 references indexed in Scilit:
- Biological effects of paragonial substances PS-1 and PS-2, in females of Drosophila funebrisJournal of Insect Physiology, 1974
- The isolation, partial characterization, and biosynthesis of the paragonial substances, PS-1 and PS-2, of Drosophila funebrisJournal of Insect Physiology, 1974
- The effect of matrone on oviposition in the mosquito, Aedes aegyptiJournal of Insect Physiology, 1972
- Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and SacBiochemistry, 1971
- The partial purification and separation of the protein components of matrone from Aedes aegyptiJournal of Insect Physiology, 1970
- Paragonial substance (sex peptide) and other free ninhydrin-positive components in male and female adults of Drosophila melanogasterJournal of Insect Physiology, 1970
- The protein nature of the substance inducing female monogamy in Aedes aegyptiJournal of Insect Physiology, 1969
- The control of sexual receptivity in female DrosophilaAnimal Behaviour, 1967
- A sex-specific ninhydrin-positive substance found in the paragonia of adult males of Drosophila melanogasterJournal of Insect Physiology, 1961
- Sex Peptide of Drosophila melanogasterScience, 1959