Obesity and Estrogen as Risk Factors for Gastroesophageal Reflux Symptoms
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Open Access
- 2 July 2003
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 290 (1) , 66-72
- https://doi.org/10.1001/jama.290.1.66
Abstract
Gastroesophageal reflux disease and obesity are both highly prevalent in Western societies, and the occurrence of these conditions is rapidly increasing.1-7 Reflux has an adverse impact on quality of life,8 and the costs for long-term antireflux medication are high.9 Reflux symptoms10-12 and obesity13,14 are strong and independent risk factors for esophageal adenocarcinoma, a cancer that has increased significantly in incidence during recent decades.15,16Keywords
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