Estrogen Target Sites in the Brain of the Chick Embryo
- 26 December 1975
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 190 (4221) , 1307-1308
- https://doi.org/10.1126/science.173022
Abstract
Autoradiograms prepared from brains of chick embryos after injection of [3H]estradiol demonstrate the existence of target cells for estrogen in the medial preoptic and ventral hypothalamic regions as early as day 10 of incubation. Target cells also appear in telencephalic locations during later stages of embryonic development. These hormone-concentrating cells probably are the anatomical substrate for the formative action of sex steroids during embryonic life on certain brain functions such as control of sexual and aggressive behaviour and gonadotropin secretion.Keywords
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