Enzymatic preparation of optically active precursors of CPI, the DNA alkylation subunit of the naturally occurring antitumour antibiotic CC-1065
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 13,p. 1559-1560
- https://doi.org/10.1039/cc9960001559
Abstract
Some immediate precursors of CPI, the DNA alkylation subunit of CC-1065 are subjected to enzymatic resolution with Lipase PS in vinyl acetate; racemic 3 is effectively resolved by two consecutive enzymatic reactions.Keywords
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