CORRELATION OF VISUAL EVOKED POTENTIALS, OPHTHALMOLOGICAL AND NEUROLOGICAL FINDINGS AFTER UNILATERAL OPTIC NEURITIS

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Abstract
Patients (42) were tested with pattern reversal visual evoked potential (VEP) 1-8 yr after an episode of acute unilateral optic neuritis. The stimulation was produced by dot and checker-board patterns. An unexpectedly large proportion (12 cases) showed normal VEP latencies from the affected eye. In these patients the initial visual acuity was usually significantly better than in cases with prolonged VEP latencies. They had significantly fewer remaining ocular signs than the patients with abnormal VEP. No correlation was found between the VEP and the incidence of CSF abnormalities, multiple sclerosis and HLA types. In 14 patients, 13 belonging to the group above, repeated VEP tests were performed from the acute onset of the disease up to 2 yr afterwards. A considerable normalization of VEP latencies occurred.