Influence of Catalin® (1-Hydroxy-pyrido-(3,2α)-5-phenoxazone-3-carboxylic acid) on the Sorbitol Content of Incubated Bovine Lenses

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Abstract
48 h incubation of bovine lenses was performed in which one lens of a pair was subjected to Catalin® (0.6 × 10––4 M), the other serving as control. Subsequently, the sorbitol concentrations were determined. Lenses under the influence of Catalin showed a significantly decreased concentration in sorbitol. The possible mode of action is discussed.