Bio-Bar-Code-Based DNA Detection with PCR-like Sensitivity
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- 27 April 2004
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 126 (19) , 5932-5933
- https://doi.org/10.1021/ja049384+
Abstract
Novel two-component oligonucleotide-modified nanoparticle probes have been designed and used in a bio-bar-code assay with a 500 zeptomolar target DNA sensitivity limit.Keywords
This publication has 13 references indexed in Scilit:
- Gold nanoparticle-based detection of genomic DNA targets on microarrays using a novel optical detection systemBiosensors and Bioelectronics, 2003
- Particle Formation by Ion Nucleation in the Upper Troposphere and Lower StratosphereScience, 2003
- p24 Antigen Detection Assay Modified with a Booster Step for Diagnosis and Monitoring of Human Immunodeficiency Virus Type 1 InfectionJournal of Clinical Microbiology, 2003
- A PCR-based amplification method retaining the quantitative difference between two complex genomesNature Biotechnology, 2002
- Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problemsJournal of Molecular Endocrinology, 2002
- Efficient Near-Infrared Polymer Nanocrystal Light-Emitting DiodesScience, 2002
- Combining nucleic acid amplification and detectionCurrent Opinion in Biotechnology, 2001
- A Fluorescence-Based Method for Determining the Surface Coverage and Hybridization Efficiency of Thiol-Capped Oligonucleotides Bound to Gold Thin Films and NanoparticlesAnalytical Chemistry, 2000
- Scanometric DNA Array Detection with Nanoparticle ProbesScience, 2000
- Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell AnemiaScience, 1985