COMPARISON OF CYTOCHROME-C STRUCTURE IN CRYSTAL AND IN SOLUTION BY LARGE-ANGLE X-RAY-SCATTERING

  • 1 January 1981
    • journal article
    • research article
    • Vol. 26  (1) , 32-36
Abstract
Large-angle X-ray diffuse scattering was used to study the conformational changes in [pig heart] cytochrome c during its transition from crystal into solution and during a change of the electron state of the heme. The structure of cytochrome c in solution differs from its structure in crystal form by a shift of the chain fragment in the region of 60-77 amino acid residues. The studies of the oxidized, reduced and cyanoforms of the protein in solution did not reveal noticeable changes in the protein structure.

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