NEONATAL LOW-LEVEL LEAD-EXPOSURE IN MONKEYS (MACACA FASCICULARIS) - EFFECT ON 2-CHOICE NON-SPATIAL FORM DISCRIMINATION

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  • 1 January 1979
    • journal article
    • research article
    • Vol. 2  (4) , 1195-1203
Abstract
Monkeys were dosed orally with 500 .mu.g/kg per day of Pb as lead acetate from day 1 of life. No overt signs of Pb toxicity were observed. At 2-3 yr of age they were tested on a 2-choice nonspatial form discrimination using a Wisconsin General Testing Apparatus. Treated monkeys showed deficits compared to controls on a series of 20 discrimination reversals; there was no difference between the groups in the effect of a series of overtraining trials introduced between reversals.

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