Remission of progressive multifocal leucoencephalopathy in SLE after treatment with cidofovir: a 4 year follow up

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Abstract
We report a 40 year old woman diagnosed with SLE at the age of 20 years, based on four American College of Rheumatology criteria (erythema, arthritis, elevated antinuclear antibodies, and anti-dsDNA antibodies). Owing to neuropsychiatric lupus (the patient had experienced several psychotic episodes) with suspected vasculitic changes on cerebral magnetic resonance imaging (MRI), the patient had undergone 12 cycles of cyclophosphamide pulse therapy in 1995/96 followed by immunosuppressive treatment with mycophenolate mofetil in 1998, and azathioprine in 1999. Follow up cerebral MRI scans at that time were normal.

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