Fusarium Meningoencephalitis in a Child with Acute Leukemia
- 1 May 1991
- journal article
- case report
- Published by Georg Thieme Verlag KG in Neuropediatrics
- Vol. 22 (02) , 110-112
- https://doi.org/10.1055/s-2008-1071428
Abstract
A 15-year-old boy with acute lymphoblastic leukemia (ALL) developed disseminated fusarium infection with meningoencephalitis following a contaminated skin wound. With antifungal therapy, the cutaneous lesions cleared but central nervous system (CNS) infection persisted causing a fibrosing meningitis and a brain granuloma. Fusaria are soil saprophytes that are more commonly associated with superficial eye and skin lesions, but may also cause severe systemic infections with CNS involvement in immuno-compromised patients. The organism may be confused with Aspergillus in tissue sections, and can only be diagnosed by culture.Keywords
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