STUDIES OF ENVIRONMENTAL AND HOST FACTORS INFLUENCING PERSONAL DIFFERENCES IN RESPONSE TO INDUSTRIAL SILICA DUST EXPOSURE
- 1 December 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Annals of Occupational Hygiene
- Vol. 26 (8) , 745-752
- https://doi.org/10.1093/annhyg/26.8.745
Abstract
Factors associated with personal differences in response to silica dust exposure were investigated in a preliminary way in Quebec metal mines by studying clinical records, medical and occupational histories for all 203 men compensated for silicosis (‘silicotics’) by the Quebec Workers' Compensation Commission between 1967 and 1977 together with 102 non-silicotic metal miners. A significantly ( P P <0.001) larger proportion (8.4%) of the silicotics than the non-silicotics (2.0%) had history of immunologic abnormalities, but only 3.5% of the silicotics had a history of the abnormalities prior to the diagnosis of silicosis. Differences in responses of the silicotic and non-silicotic miners appeared to be mostly due to differences in actual exposures coupled with the possible effect of the differences in immune factors.Keywords
This publication has 0 references indexed in Scilit: