Neurotoxic and Nephrotoxic Effects of Colistin in Patients with Renal Disease
- 12 April 1962
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 266 (15) , 759-762
- https://doi.org/10.1056/nejm196204122661505
Abstract
COLISTIN is an antibiotic which, although similar to polymyxin B in chemical structure and antimicrobial spectrum, produces significantly fewer toxic reactions in man. The present report describes potentially serious reactions to colistin§ in 3 adults with impaired kidney function and in a child who was given ten times the recommended dosage.Case ReportsCase 1. S.S., a 13-year-old white boy, was admitted to the hospital for treatment of a refractory chronic otitis media associated with pseudomonas. His weight was 42.6 kg. (94 pounds). Although colistin was prescribed in a dosage of 25 mg. every 6 hours he was inadvertently given . . .Keywords
This publication has 3 references indexed in Scilit:
- COLISTINThe Lancet Healthy Longevity, 1960
- TOXICITY OF POLYMYXIN BA.M.A. Archives of Internal Medicine, 1953
- Use of Polymyxin in Gram Negative Urinary Tract InfectionsJournal of Urology, 1949