Catalytically Active Species for CeCI3-Induced DNA Hydrolysis1

1 May 1994

journal article
research article
Published by Oxford University Press (OUP) in The Journal of Biochemistry

Vol. 115 (5) , 809-810
https://doi.org/10.1093/oxfordjournals.jbchem.a124419

Abstract

Cerium(III) chloride efficiently hydrolyzes DNA at pH 7 under aerobic conditions. A titration study showed that Ce(III) is oxidized to Ce(IV) in the reaction mixture and the resultant Ce(IV) is responsible for the DNA hydrolysis.

Keywords

ARTIFICIAL RESTRICTION ENZYME
CERIUM(III) CHLORIDE
CE(IV) ION
DNA HYDROLYSIS

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