Ultrastructure of Normal Rabbit Mesentery

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Abstract
The ultrastructure of the mesentery was examined by EM after in vivo fixation in 7 normal rabbits. In 1, the fixation was performed after i.v. injection of an electron-dense tracer (Fe dextran) and i.p. infusion of dialysate 4.25% for 1 h. Morphometric data of the active peritoneal dialysis membrane, i.e., capillary endothelial cells, interstitium and mesothelial cells were studied. The mesothelial cells are flattened and overlapping with tight junctions between them. They lie on a continuous basement membrane and they contain numerous intracytoplasmic vesicles, separated or in clusters. The mesenteric microvessels were mainly true capillaries of continuous type and postcapillary venules. Capillary lymphatics and larger lymphatic channels (lacunae) seem to be more extensive than the blood capillaries and venules. The endothelial cells contain many vesicles. The interstitium consists of bundles of collgen, fibroblasts and occasional macrophages. The electron-dense tracer was found in the vesicles of the mesothelial cells suggesting that vesicular transport may play an important part in the transportation of at least molecules of a certain size.

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