Amino acid composition of dermal-collagen fractions in rats of different ages

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Abstract
Purified neutral-salt-soluble, citrate-soluble and insoluble fractions of rat-skin collagen were obtained from newborn, young, adult and senile animals, and the amino-acid compositions determined. The amino-acid composition of the different collagen fractions remained fairly constant during the aging process. The ratio proline/hydroxyproline was lower in newborn animals thaninthose of other ages. The average amino-acid values obtained are in good agreement with previously published analyses.