Liver Inclusions in Erythropoietic Protoporphyria
- 1 February 1975
- journal article
- Published by Wiley in European Journal of Clinical Investigation
- Vol. 5 (1) , 21-26
- https://doi.org/10.1111/j.1365-2362.1975.tb00424.x
Abstract
Needle-like inclusions have been found, by electron microscopy, in the livers of two unrelated patients with erythropoietic protoporphyria. Since they have not been noted in other hepatic conditions but do occur in the livers of protoporphyric mice it is suggested that they represent markers for protoporphyric liver disease. Paracrystalline inclusions that have been previously described in Wilson's disease and porphyria cutanea tarda were also present in the hepatocytes of one of these patients.Keywords
This publication has 17 references indexed in Scilit:
- Erythropoietic protoporphyria with features of a sideroblastic anaemia terminating in liver failureThe American Journal of Medicine, 1973
- ERYTHROPOIETIC PROTOPORPHYRIA: TWO DEATHS FROM HEPATIC CIRRHOSISBritish Journal of Dermatology, 1971
- Histopathologie und Ultrastruktur der Haut bei ProtoporphyrinämieVirchows Archiv, 1971
- Erythropoietic protoporphyria: evidence for multiple sites of excess protoporphyrin formationJournal of Clinical Investigation, 1971
- Factors Affecting the Induction of Porphyria in the Laboratory Rat. Biochemical and Photobiological Studies Using Diethyl 1,4-dihydro-2,4,6-trimethyl-pyridine-3,5-dicarboxylate (DDC) as a Porphyrogenic Agent*Journal of Investigative Dermatology, 1969
- ELECTRON MICROSCOPY OF THE SKIN IN ERYTHROPOIETIC PROTOPORPHYRIABritish Journal of Dermatology, 1968
- Erythropoietic porphyrin hepatitisJournal of Clinical Pathology, 1968
- HISTOCHEMISTRY OF THE SKIN IN ERYTHROPOIETIC PROTOPORPHYRIA*British Journal of Dermatology, 1966
- Erythropoietic protoporphyria. III. PhotohemolysisArchives of Dermatology, 1966
- Filamentous inclusions in the matrix of mitochondria from human liversJournal of Ultrastructure Research, 1964