Gaba‐antagonists alter spatial summation in receptive field centres of rod‐ but not cone‐drive cat retinal ganglion Y‐cells.

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Abstract
When Y-type cat retinal ganglion cells were driven by cones, the i.v. administration of the GABA-antagonist picrotoxin failed to alter receptive field center size. This result was in marked contrast to the previous finding that, when Y-cells were driven by rods, GABA-antagonists led to specific and reversible changes in center size. Collectively, these results suggest that, for center signals of Y-cells, the rod and cone pathways are pharmacologically distinct.