Plasma Oxytocin Concentrations in Man after Different Routes of Administration of Synthetic Oxytocin
- 1 April 1985
- journal article
- research article
- Published by Georg Thieme Verlag KG in Experimental and Clinical Endocrinology & Diabetes
- Vol. 85 (02) , 245-248
- https://doi.org/10.1055/s-0029-1210444
Abstract
Plasma oxytocin was determined by RIA in three male subjects under basal conditions and following administration of synthetic oxytocin. As compared to basal levels (below 10pg/ml), plasma oxytocin was found to be elevated markedly (36 to 85 pg/ml) in response to application by nasal spray (total dose: 65 to 100 µg). Intramuscular injection (25 µg) resulted in very high oxytocin levels (360 to 480 pg/ml), whereas buccal administration (70 µg) was proved to be ineffective (levels below 10 pg/ml plasma). In each case, plasma vasopressin remained unchanged.Keywords
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