Severe Tissue Damage following Accidental Subcutaneous Infusion of Bicarbonate Solution

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Abstract
Four patients with severe necrosis of superficial and deep tissue following subcutaneous leakage of 8.4% sodium bicarbonate solution during successful resuscitation were seen. In all patients necrosis was extensive involving skin, subcutaneous tissue, deep fascia, muscle, regional veins and adjacent superficial nerves.

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