Cellular interactions in haematopoiesis

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Abstract
In vitro culture of hematopoietic cells has provided some surprising insights into critical interactions of blood-forming cells. Subpopulations of lymphoid cells produce colony-stimulating activity, interact with macrophages, and have important effects on the very early stages of erythropoiesis. Macrophages have multiple influences on the proliferation and differentiation of other hematopoietic cells.