Endometrial Blood Flow in Anaesthetized Sheep as Measured with Krypton-85 Clearance and Microsphere Techniques
- 22 January 1980
- journal article
- research article
- Published by Wiley in Quarterly Journal of Experimental Physiology and Cognate Medical Sciences
- Vol. 65 (1) , 19-26
- https://doi.org/10.1113/expphysiol.1980.sp002488
Abstract
Uterine blood flow rates were obtained with a 85Kr clearance technique and with radioactive microspheres in 6 anesthetized, non-pregnant ewes (a total of 10 comparisons). 85Kr was administered via a catheter into the abdominal aorta and .beta.-emissions were detected with a catheter -type semi-conductor detector probe situated in the lumen of a uterine horn. In 7 instances the 85Kr clearance curve had only 1 component while in the remaining 3 instances the curves were resolved into 2 components. The flow rates derived from the single component curves and the mean flow rates calculated from the curves with 2 components were of the same order as, and highly correlated with estimates of capillary blood flow obtained with microspheres for the caruncles, the inter-caruncular endometrium or the total endometrium (r [correlation coefficient] = 0.832, 0.822 and 0.841, respectively, P < 0.005). There was no correlation between the flow rates obtained with the 85Kr technique and estimates of myometrial capillary blood flow obtained with microspheres.This publication has 1 reference indexed in Scilit: