Cytotoxic and Antimalarial Alkaloids from the Bulbs of Crinum amabile
- 1 August 1993
- journal article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 56 (8) , 1331-1338
- https://doi.org/10.1021/np50098a017
Abstract
From the bulbs of Crinum amabile (Amaryllidaceae), a new alkaloid (-)-amabiline [1], together with the known alkaloids (-)-lycorine [2], (-)-buphanisine [3], (-)-augustine [4], and (+)-crinamine [5], were isolated. The structural characterization of 1 and the revised 1H- and 13C-nmr assignments of 2 are discussed. Alkaloids 2, 4, and 5 were found to be the principal cytotoxic and antimalarial constituents.Keywords
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