Structure-based drug design of nonpeptidic P2 substituents for HIV-1 protease inhibitors
- 1 April 1995
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 5 (7) , 727-732
- https://doi.org/10.1016/0960-894x(95)00103-z
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- New dipeptide isosteres useful for the inhibition of HIV-1 proteaseBioorganic & Medicinal Chemistry Letters, 1994
- The HIV-1 Protease as a Therapeutic Target for AIDSAIDS Research and Human Retroviruses, 1992
- HIV protease: a novel chemotherapeutic target for AIDSJournal of Medicinal Chemistry, 1991
- Design of enzyme inhibitors using iterative protein crystallographic analysisJournal of Medicinal Chemistry, 1991
- Structure-based, C2 symmetric inhibitors of HIV proteaseJournal of Medicinal Chemistry, 1990
- Rational Design of Peptide-Based HIV Proteinase InhibitorsScience, 1990
- A Synthetic HIV-1 Protease Inhibitor with Antiviral Activity Arrests HIV-Like Particle MaturationScience, 1990
- Conserved Folding in Retroviral Proteases: Crystal Structure of Synthetic HIV-1 ProteaseScience, 1989
- Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDSScience, 1984
- Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)Science, 1983