AGE-RELATED-CHANGES IN HUMAN THYMUS
- 1 January 1979
- journal article
- research article
- Vol. 37 (3) , 507-511
Abstract
Thymic biopsies obtained during open heart surgery were examined for age-related involution of the parenchyma and changes in cell surface characteristics. In parallel with the parenchymal atrophy, E[sheep erythrocyte]-rosette-forming cells continuously decreased with age and were progressively replaced by an increasing proportion of ''null'' lymphoid cells. These changes appeared independent of each other. The significance of these findings in the context of the host''s immune mechanism is discussed.This publication has 13 references indexed in Scilit:
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