Isolation of Lignans and Sesquiterpenoids from Leaves ofZanthoxylum Naranjillo

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Abstract
From the hexane crude extract of the leaves of Zanthoxylum naranjillo, fourteen compounds were isolated. Three sesquiterpenes: β-selinene, α-cyperone and (-)-juniper camphor; four furofuran lignans: (+)-sesamin, (-)-pluviatylol-4′-O-γ,γ-dimethylallyl ether, (-)-xanthoxylol-4′-O-γ,γ-dimethylallyl ether, (+)-piperitol-4′-O-γ,γ-dimethylallyl ether; four dibenzylbutyrolactone lignans: (-)-hinokinin, (-)-hibalactone, (-)-methylpluviatolide, (-)-kaerophylin; two furan lignans: (-)-cubebin and (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin. Sitosterol was also present. These compounds were isolated for the first time from Z. naranjillo.