Bulk magnetic susceptibility induced broadening in the 19F NMR of suspended leukemic cells
- 1 March 1993
- journal article
- research article
- Published by Wiley in NMR in Biomedicine
- Vol. 6 (2) , 125-129
- https://doi.org/10.1002/nbm.1940060204
Abstract
The relevance of bulk magnetic susceptibility (BMS) induced broadening to in vivo NMR studies of intact cells has been examined and the significance of the contribution of BMS difference to the resolution of intra- and extracellular resonances was demonstrated. BMS difference between intra- and extracellular compartments was found to limit the resolution of intra- and extracellular 19F resonances of fluoro compounds in leukemic cells.Keywords
This publication has 14 references indexed in Scilit:
- 13CNMR studies of glucose metabolism in human leukemic CEM‐C7 and CEM‐C1 cellsMagnetic Resonance in Medicine, 1992
- The phenomenon of separate intra‐ and extracellular resonances of difluorophosphate in 31P and 19F NMR spectra of erythrocytesMagnetic Resonance in Medicine, 1991
- Bulk magnetic susceptibility shifts in nmr studies of compartmentalized samples: use of paramagnetic reagentsMagnetic Resonance in Medicine, 1990
- Calculation and interpretation of inhomogeneous line broadening in models of lungs and other heterogeneous structuresJournal of Magnetic Resonance (1969), 1989
- Determination of membrane potential and cell volume by fluorine-19 NMR using trifluoroacetate and trifluoroacetamide probesBiochemistry, 1989
- Physical basis of the effect of hemoglobin on the phosphorus-31 NMR chemical shifts of various phosphoryl compoundsBiochemistry, 1988
- Hypophosphite ion as a 31P nuclear magnetic resonance probe of membrane potential in erythrocyte suspensionsBiophysical Journal, 1988
- Measurement of intracellular pH and deoxyhemoglobin concentration in deoxygenated erythrocytes by phosphorus-31 nuclear magnetic resonanceBiochemistry, 1984
- The effect of compartmental location on the proton T2∗ of small molecules in cell suspensions: A cellular field gradient modelJournal of Magnetic Resonance (1969), 1983
- Effect of magnetic susceptibility on nuclear magnetic resonance signals arising from red cells: a warningBiochemistry, 1983