Low frequency of FLT3 gene internal tandem duplication and activating loop mutation in therapy-related acute myelocyticleukemia and myelodysplastic syndrome

This publication has 12 references indexed in Scilit:

• CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated withFLT3 internal tandem duplication
  Blood, 2003
• Aberrant p15 gene promoter methylation in therapy‐related myelodysplastic syndrome and acute myeloid leukaemia: clinicopathological and karyotypic associations
  British Journal of Haematology, 2003
• Studies of FLT3 mutations in paired presentation and relapse samples from patients with acute myeloid leukemia: implications for the role of FLT3 mutations in leukemogenesis, minimal residual disease detection, and possible therapy with FLT3 inhibitors
  Blood, 2002
• The roles of FLT3 in hematopoiesis and leukemia
  Blood, 2002
• Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis
  Blood, 2002
• Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia
  Blood, 2002
• Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy
  Leukemia, 2001
• FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia
  Blood, 2001
• Mutations With Loss of Heterozygosity of p53 Are Common in Therapy-Related Myelodysplasia and Acute Myeloid Leukemia After Exposure to Alkylating Agents and Significantly Associated With Deletion or Loss of 5q, a Complex Karyotype, and a Poor Prognosis
  Journal of Clinical Oncology, 2001
• Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia
  Leukemia, 1997