Comparison of prolactin concentrations between haloperidol and risperidone treatments in the same female patients with schizophrenia

Abstract
The present study aimed to investigate intraindividual changes in plasma prolactin concentrations by switching from haloperidol treatment to risperidone treatment. The subjects were 15 female schizophrenic inpatients who received firstly haloperidol 12 mg/day for at least 2 weeks and, thereafter, risperidone 6 mg/day. Prolactin concentration in plasma during risperidone treatment (median 87.5 ng/ml, range 5.3–298.1 ng/ml) was significantly (PPPP2 receptor, compared with the broader pharmacological spectrum of risperidone.

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