Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein

This publication has 29 references indexed in Scilit:

• An investigation of persistent microfilaridermias despite multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana
  Pathogens and Global Health, 2004
• Final report of the Conference on the eradicability of Onchocerciasis
  Filaria Journal, 2003
• Effects of standard and high doses of ivermectin on adult worms of Onchocerca volvulus: a randomised controlled trial
  The Lancet, 2002
• Identification and stage-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus
  Molecular and Biochemical Parasitology, 1999
• Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog1Note: Nucleotide sequence data reported in this paper have been submitted to the GenBank data base with the accession number AF 003908.1
  Molecular and Biochemical Parasitology, 1998
• Reversal of P-glycoprotein-associated multidrug resistance by ivermectin
  Biochemical Pharmacology, 1997
• The abamectin derivative ivermectin is a potent P-glycoprotein inhibitor
  Anti-Cancer Drugs, 1996
• Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.
  Journal of Clinical Investigation, 1995
• Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
  Published by Elsevier ,1994
• ABC Transporters: From Microorganisms to Man
  Annual Review of Cell Biology, 1992