Adenosine 3′,5′-Monophosphate Phosphodiesterase: Multiple Molecular Forms
- 6 August 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 173 (3996) , 540-542
- https://doi.org/10.1126/science.173.3996.540
Abstract
By starch-gel electrophoresis and a specific staining technique, seven different molecular forms of cyclic nucleotide phosphodiesterase have been demonstrated in supernatants from homogenates of rat and rabbit tissues. No tissue contains more than four components, but there are distinct differences in component patterns among the various tissues. Tentative molecular weights of the three most prevalent components of rat tissues have been estimated at 135,000, 150,000, and 167,000 by sucrose density gradient centrifugation.Keywords
This publication has 8 references indexed in Scilit:
- Cyclic 3′,5′-nucleotide phosphodiesterase, IV. Two enzymes with different properties from brainBiochemical and Biophysical Research Communications, 1971
- Presence of two 3′–5′-cyclic AMP phosphodiesterases in rat kidney and frog bladder epithelial cells extractsBiochemical and Biophysical Research Communications, 1970
- Preparation and properties of a cyclic 3′,5′-nucleotide phosphodiesterase isolated from frog erythrocytesArchives of Biochemistry and Biophysics, 1970
- Macromolecular forms of aspartate transcarbamylase in rat liverBiochemical and Biophysical Research Communications, 1969
- Cyclic 3′,5′-nucleotide phosphodiesteraseAnalytical Biochemistry, 1969
- Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)Circulation, 1968
- Adenosine 3‘,5‘-Phosphate in Biological MaterialsJournal of Biological Chemistry, 1962
- STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. III. PYRIDINE NUCLEOTIDES*Journal of Clinical Investigation, 1962