Transvaginal Roentgen Therapy in the Conservative Management of Carcinoma in Situ of the Uterine Cervix

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Abstract
The alterations of the epithelium of the cervix known as carcinoma in situ (Fig. 1) have been recognized for over half a century (4, 20, 22), but only in the last twenty years has serious consideration been given to the proper identification, to the study of the course, and to the definitive treatment of this lesion. The work of Papanicolaou and Traut (14) made possible the early detection and diagnosis of carcinoma in situ in asymptomatic patients. The course of these pathologic changes has been studied by Younge et al. (26), Galvin and TeLinde (5, 24) and various other authors. The definitive treatment of carcinoma in situ has varied considerably, but the reports of results, since the earliest trials, have been very favorable. Hysterectomy has been widely accepted and practiced, although this operation is unduly radical for a lesion that is only potentially invasive. The chance of eventual transformation into invasive carcinoma has been reported as varying from 13 per cent (8, 9) to 35 per cent (17) if ...

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