Isolation and characterization of bulgecins, new bacterial metabolites with bulge-inducing activity.
- 1 January 1985
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 38 (1) , 17-23
- https://doi.org/10.7164/antibiotics.38.17
Abstract
Bulgecins A, B and C, new bacterial metabolites which induce the formation of bulges by cooperation with .beta.-lactam antibiotics, were isolated from the culture broth of Pseudomonas mesoacidophila. The 3 components, separated by column chromatography on QAE-Sephadex A-25, are water-soluble acidic compounds containing a sulfate group in the molecule. Acid hydrolysis showed that D-glycosamine and a new proline derivative are common constituents of the 3 components. Taurine and .beta.-alanine are constituents of bulgecins A and B, respectively.This publication has 6 references indexed in Scilit:
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